You are not withdrawing any bacteriostatic water at this point while holding the barrel of the syringe, insert the needle through the rubber stopper of the water. Sterile water for injection usp is a clear, colorless, odorless liquid. Bacteriostatic water bacteriostatic water for injection is a highly purified, sterilized water containing 0. Administer as a subcutaneous injection once daily after the lyophilized cake is reconstituted with bacteriostatic water for injection bwfi or preservativefree sterile water for injection wfi. Bacteriostatic sterile water bacteriostatic water 30ml. The solution from the 4mg multidose vial, reconstituted with bacteriostatic water for injection, usp, can be stored refrigerated for up to 14 days. Sermorelin comes in powder form, freezedried, which is called lyophilized, bacteriostatic water is added to it, and the powder dissolves and. Important use only the accompanying diluent or bacteriostatic water for injection with benzyl alcohol when reconstituting solumedrol.
Mediatech 25055cvc cell culture grade water tested to usp sterile water for injection specifications with septum cap pack of 6 3. Bacteriostatic water for injection, usp is a sterile, nonpyrogenic preparation of bacteriostatic water for injection packaged in multiple dose. Bacteriostatic sodium chloride fda prescribing information. Save 15% when you buy this allinclusive kit versus buying each item separately. Caverject impulse dual chamber system alprostadil for injection.
Pfizer recommends that after this time you must discard the vial. It is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of. Hospira bacteriostatic water 30ml 30ml multipledose plastic vial description the following preparation is designed solely for parenteral use only after addition of drugs that require dilution or must be dissolved in an aqueous vehicle prior to injection. Table 1 summarises the main categories of sterile products. Bacteriostatic water for injection is made under sterile condition to meet the national and international medial standards. Purchase bacteriostatic water, insulin syringes and more. Where water for injection is required for preparing or.
Bacteriostatic water for injection, usp by hospira medline. Parenteral drug products should be inspected visually for particulate matter and. It is different from sterile water, which is filtered and purified but has no additives, and is usually only. Do not reconstitute or dilute with bacteriostatic water for injection, usp or dilute with bacteriostatic sodium chloride injection, usp.
Bacteriostatic water can be used multiple times up to 28 days once opened. Benzyl alcohol, a preservative in bacteriostatic water for injection, usp has been associated with toxicity in neonates. Oct 26, 2020 the following preparation is designed solely for parenteral use only after addition of drugs that require dilution or must be dissolved in an aqueous vehicle prior to injection. Do not use bacteriostatic water for injection, usp for intravenous injection unless the osmolar concentration of additives results in an approximate isotonic admixture. Bluegill npdes lc50 96 hours 10 mgl rabbit dermal ld 50 2gmkg daphnia magna water flea surrogate erc50 48 hours 23 400 mgl version. Buy bacteriostatic water bac from licensed drug store or website. The small volume of fluid provided by sterile water for injection, usp or bacteriostatic water for injection, usp when used only as a pharmaceutic aid for diluting or dissolving drugs for parenteral injection, is unlikely to exert a significant effect on fluid balance except. Buy bacteriostatic water online bac 10ml swiss chems. Bacteriostatic water for injection summary of product.
Caverject impulse is available as a disposable, singledose, dual chamber syringe system. If a precipitate forms, cool in an notefor microbiological guidance, see general information ice bath to room temperature, and pass through a sinteredchapter water for pharmaceutical purposes. May 17, 2006 a vial with diluent mixing liquid bacteriostatic water for injection containing benzyl alcohol as preservative for omnitrope 5. In the workplace, this material should be considered potentially irritating to the eyes and respiratory tract. Sterile water for injection usp is a diluent or solvent suitable for intravascular injection after first having been made approximately isotonic by the addition of suitable solute. Bacteriostatic water is used to dilute or dissolve medications for patient injection. In the workplace, this material should be considered potentially. Bacteriostatic water is a water based substance, which is made up of largely sterile water with 0. The preservative benzyl alcohol may cause hypersensitivity reactions. Solumedrol methylprednisolone sodium succinate for. Guideline on water for pharmaceutical use european medicines. Diluent bacteriostatic water, usp for intramuscular, intravenous or subcutaneous injection multidose vial for superior convenience. Highlights of prescribing information after suspected or.
Iv push information draft 2017 10 23 drug indicated. Benzyl alcohol based, designed for injection mixes bacteriostatic water for injection contains 0. This substance is primarily used for the dissolution or dilution of medicines. Once a vial of bacteriostatic water is opened, the benzyl alcohol will usually prevent the growth of bacteria for up to 28 days. Watermed bac teriostatic water for injections is a sterile, nonpyrogenic preparation of water for injection containing 0. To boil water for injection use, use a clean pot with a lid.
May 08, 2018 example 1mlcc bacteriostatic water per 2mg pt141 vial equates to a 1mg dose approximately every 50 units on a u100 insulin syringe. Bacteriostatic sterile water bacteriostatic water bacteriostatic water 30ml sterile sealed. Intravenous administration of benzyl alcohol has been associated with serious adverse events, and death in paediatric. Each milliliter ml contains sodium chloride 9 mg and 0.
Initial reconstitution of nplate with designated volumes of sterile water for injection, usp results in a concentration of 500 mcgml in all vial sizes. What to know about bacteriostatic sterile water for injection. Sterile purified water bacteriostatic water for injection sterile water for inhalation sterile water for injection apparatus limit of detection 100ppb system suitability test reagent water toc level. Water is multifunctional raw material solvent ingredient reagent cleaning agent hot water or steam sterilepackaged waters sterile water for irrigation sterile water for inhalation sterile purified water bacteriostatic water for injection water for hemodialysis availability of water will be a bigger challenge than. Sterile water for injection, usp, is sterile, nonpyrogenic, distilled water in a single dose container for intravenous administration after addition of a suitable solute. Prescribed cjc1295ipamorelin vial amount of bacteriostatic water to add 6 mg15 mg vial add 6. If sensitivity to the diluent occurs, may be reconstituted with sterile water for injection, usp.
Mediatech 25055ci cell culture grade water tested to usp sterile water for injection specifications, 100 ml pack of 6 4. It is supplied in a multipledose container from which repeated withdrawals may be made to dilute or. Rt 24 hrs 5c 96 hrs vial size diluent to be added approx. Bacteriostatic water for injection, usp must be made approximately isotonic prior to use. The bacteriostatic water for injection is used for diluting the powered medicine. For intramuscular, intravenous or subcutaneous injection. Liquid solutions containing benzyl alcohol including leukine injection or leukine for injection reconstituted with bacteriostatic water for injection, usp 0. A recommended strategy for mixing and dosing would be to reconstitute with the volume that yields a. Bacteriostatic water for injection, usp by hospira. Complete the infusion within 6 hours of reconstitution.
The diluent contains bacteriostatic water for injection with 0. Bacteriostatic water for injections contains benzyl alcohol see section 2. If a precipitate forms, cool in an if a precipitate forms, cool in an note for microbiological guidance, see general information ice bath to room temperature, and pass through a sintered. While you certainly cant drink it, it does have usefulness in the body when helping to recover from ailments. Bacteriostatic water for injection, usp is a sterile, nonpyrogenic preparation of water for injection containing 0. The benzyl alcohol in the water makes bacteriostatic water ideal for diluting any drug that will be administered by intramuscular, intravenous, or subcutaneous injection. Bacteriostatic water for injection has an extra preservative agent added into the water called benzyl alcohol bnoh. Bacteriostatic water in stock hospira 30ml multidose vial. Bacteriostatic water for injection is sterile, nonpyrogenic water that contains 0.
Dec 21, 2020 before you can inject daily doses of sermorelin, the first thing you need to do is reconstitute the product from lyophilized powder form to a liquid before preparing it for injection into your body. Caverject impulse dual chamber system alprostadil for. Bacteriostatic water for injection fda prescribing. Data are unavailable on the toxicity of other preservatives in this age group.
The use of toc measurements for process control in. It means that it inhibits the growth of any contaminating bacteria in the water. Bacteriostatic water for injection, usp contains parabens not for use in newborns. Jul 15, 2020 bacteriostatic water is a type of sterile water that contains 0. Bacteriostatic water for injection, usp is a sterile, nonpyrogenic preparation of bacteriostatic water for injection packaged in multiple dose vials. It is supplied in a multipledose container from which repeated withdrawals may be made to dilute or dissolve drugs for injection. Oct 23, 2020 if you have taken a closer look at injection water, you likely will notice that it is a lot different from tap water. Volume 24910 6332324910 10 ml in a10 ml multipledose vial 24930 6332324930 30 ml in a 30 ml multipledose vial packaged in trays of twentyfive. The small volume of fluid provided by sterile water for injection, usp or bacteriostatic water for injection, usp when used only as a pharmaceutic aid for diluting or dissolving drugs for parenteral injection, is unlikely to exert a significant effect on fluid balance except possibly in newborns or very small infants. Sterile purified water bacteriostatic water for injection water for hemodialysis availability of water will be a bigger challenge than climate change stanford university business school 6. Shake well to dissolve and immediately withdraw a volume equal to 15 mgkg of body weight not to exceed 1 gday and dilute in 0. At, we offer quality hospira brand bacteriostatic water and sterile water for injection for injection to purchase online that has an expiration date exceeding one year. Zomacton 10 mg reconstituted with bacteriostatic water for injection containing. Bacteriostatic water for injection, usp, 30 ml, multidose vial is a sterile, nonpyrogenic preparation of water for injection containing 0.
Water for injection, usp is chemically designated h2o. Multidose vial for superior convenience for your business. Dailymed bacteriostatic water water injection, solution. Cefazolin sodium contd1 issued 1297 preparation and. Water for injection, usp is chemically designated h 2o. Solumedrol methylprednisolone sodium succinatefor injection. Reconstituted solutions have a ph in the range of 7.
Chemical product and company identification manufacturer name and address hospira, inc. Boiling while cooking your drugs is not long enough to kill germs. Bacteriostatic water 30ml multiple dose flip top vial. Methylparaben and propylparaben are the preservatives containedin bacteriostaticwater for injection. The packaged diluent bacteriostatic water for injection contains benzyl alcohol as a preservative. Benzyl alcohol is a colorless liquid that has low toxicity, and low vapor pressure. Purchase bacteriostatic water for injection 30ml vial. Our complete injection kit contains bacteriostatic water, syringes, and alcohol prep pads everything needed for reconstitution, administration, and storage. Water for injection, usp, must be used immediately. The container can be reentered multiple times usually by a sterile needle. Reconstitute each 440 mg vial of trastuzumab with 20 ml of bacteriostatic water for. Pricing is per each important information about bacteriostatic water. Bacteriostatic water for injection, usp is a sterile, multipledose, nonpyrogenic water for injection. Supplied as a sterile, multipledose, nonpyrogenic water for injection that contains 0.
Bacteriostatic water for injection, usp hospira inc. This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered. Occasionally, after refrigeration, small colorless particles may appear in the serostim liquid. Possible target organs include the central nervous system, gastrointestinal system, respiratory system, and eyes. The small volume of fluid provided by bacteriostatic water for injection, usp when used only as a pharmaceutic aid for diluting or dissolving drugs for parenteral. When necessary, the ph of each formula was adjusted with sodium hydroxide so that the ph of the reconstituted solution is within the usp specified range of 7 to 8 and the. The drug is supplied in a multipledose container from which repeated withdrawals may be made to dilute or dissolve drugs for injection. Mixing syringes are either 5 ml or 10 ml sterile syringes. Agenda 1 introduction 2 pharmaceutical water monitoring and analysis. Watermed bacteriostatic water for injections is a sterile, nonpyrogenic preparation of water for injection containing 0. Sermorelin preparation for injection, usage instructions. Bacteriostatic water for injection, usp is a sterile, nonpyrogenic, sterile water that contains 0. Apr 14, 2019 bacteriostatic agents, including bacteriostatic water, stop bacteria reproduction but they dont typically kill off bacteria that have already taken root.
Data is unavailable on the toxicity of such preservatives in newborns. It is sterile, hypotonic, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents. Consult the manufacturers instructions for choice of vehicle, appropriate dilution or volume for dissolving the drugs to be injected, including the route and rate of injection. For patients sensitive to, serostim may be benzyl alcohol reconstituted with sterile water for injection, usp. Approximately 10% mechanical loss can be associated with reconstitution and multidose administration. Use the larger mixing syringe and draw the provided bacteriostatic water up to the correct mark on the syringe. The structural formula of alprostadil is represented below. Bacteriostatic sterile water for injection, 30ml, vial.
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